2013

• Costa P.F., Martins A., Vaquette C., Melchels F.P., Neves N.M., Gomes M.E., Hutmacher D.W., Reis R.L., Bioreactor composed of watertight chamber and internal matrix for the generation of cellularized medical implants. World Patent Application WO 2013/103306 (Applicant: A4TEC - Association for the advancement of tissue engineering and cell based technologies & therapies, Universidade do Minho, Campus de Gualtar 470-057 Braga, Portugal)
• Costa P.F., Martins A., Vaquette C., Neves N.M., Gomes M.E., Hutmacher D.W., Reis R.L., Single-step method and device for the generation of stratified tubular tissue substitutes, World Patent Application WO 2013/085404 (Applicant: A4TEC - Association for the advancement of tissue engineering and cell based technologies & therapies, Universidade do Minho, Campus de Gualtar 470-057 Braga, Portugal)

2009

• Costa P.F., Martins A., Gomes, M.E., Neves N.M., Reis R.L., Multichamber bioreactor with bidirectional perfusion integrated in culture system for tissue engineering strategies. European Patent Application EP 2009/09009863 (Applicant: A4TEC - Association for the advancement of tissue engineering and cell based technologies & therapies, Universidade do Minho, Campus de Gualtar 470-057 Braga, Portugal)

2021

• Pimenta J., Ribeiro R., Almeida R., Costa P.F., Silva M.A., Pereira B., 2021, Organ-on-chip approaches for intestinal 3D in vitro modelling, Cellular and Molecular Gastroenterology and Hepatology, doi: 10.1016/j.jcmgh.2021.08.015
• Gonçalves A.M., Moreira A,, Weber A., Williams G.R., Costa P.F., 2021, Osteochondral Tissue Engineering: The Potential of Electrospinning and Additive Manufacturing, Pharmaceutics, doi: 10.3390/pharmaceutics13070983
• Carvalho V., Sousa P., Pinto V., Ribeiro R., Costa P., Teixeira S., Lima R.., 2021, Hemodynamic Studies in Coronary Artery Models Manufactured by 3D Printing, International Conference Innovation in Engineering, doi: 10.1007/978-3-030-79165-0_19
• Onyekuru L.C., Moreira A., Zhang J., Angkawinitwong U., Costa P.F., Brocchini S., Williams G.R., 2021, An investigation of alkaline phosphatase enzymatic activity after electrospinning and electrospraying, Journal of Drug Delivery Science and Technology, doi: 10.1016/j.jddst.2021.102592

2020

• Carvalho V., Maia I., Souza A., Ribeiro J., Costa P.F., Puga H., Teixeira S.F.C.F., Lima R.A., 2020, In vitro Biomodels in Stenotic Arteries to Perform Blood Analogues Flow Visualizations and Measurements: A Review, The Open Biomedical Engineering Journal, doi: 10.2174/1874120702014010087
• Carvalho V., Rodrigues N., Ribeiro R., Costa P.F., Teixeira J.C.F., Lima R.A., Teixeira S.F.C.F., 2020, Hemodynamic study in 3D printed stenotic coronary artery models: experimental validation and transient simulation, Computer Methods in Biomechanics and Biomedical Engineering, doi: 10.1080/10255842.2020.1842377
• Moreira A., Lawson D., Onyekuru L., Dziemidowicz K., Angkawinitwong U., Costa P.F., Radacsi N., Williams G.R., 2020, Protein encapsulation by electrospinning and electrospraying, Journal of Controlled Release, doi: 10.1016/j.jconrel.2020.10.046
• Carvalho V., Rodrigues N., Ribeiro R., Costa P.F., Lima R.A., Teixeira S.F.C.F., 2020, 3D Printed Biomodels for Flow Visualization in Stenotic Vessels: An Experimental and Numerical Study, Micromachines, doi: 10.3390/mi11060549
• Velthoven M.J.J., Ramadan R., Zügel F.S., Klotz B.J., Gawlitta D., Costa P.F., Malda J., Castilho M.D., Kort L.M.O., Graaf P., 2020, Gel casting as an approach for tissue engineering of multilayered tubular structures, Tissue Engineering Part C: Methods, doi: 10.1089/ten.tec.2019.0280
• Felgueiras J., Ribeiro R., Brevini T.A.L., Costa P.F., 2020, State-of-the-art in reproductive bench science: Hurdles and new technological solutions, Theriogenology, doi: 10.1016/j.theriogenology.2020.01.067
• Campos D.F.D., Lindsay C.D., Roth J.G., Lesavage B.L., Seymour A.J., Krajina B.A., Ribeiro R., Costa P., Blaeser A., Heilshorn S.C. 2020, Bioprinting cell-and spheroid-laden protein-engineered hydrogels as tissue-on-chip platforms, Frontiers in Bioengineering and Biotechnology, doi: 10.3389/fbioe.2020.00374

2019

• Costa P.F., 2019, Translating Biofabrication to the Market. Trends in Biotechnology, doi: 10.1016/j.tibtech.2019.04.013
• Weisgrab G., Ovsianikov A., Costa P.F., 2019, Functional 3D Printing for Microfluidic Chips. Advanced Materials Technologies, doi: 10.1016/j.tibtech.2019.04.013

2018

• Lim K., Levato R., Costa P.F., Castilho M., Costa P.F., Alcala-Orozco C.R., van Dorenmalen K.M.A., Melchels F.P.W., Gawlitta D., Hooper G.J., Malda J., 2018, Bio-resin for high resolution lithography-based biofabrication of complex cell laden constructs, Biofabrication, doi.org/10.1088/1758-5090/aac00c
• Ferraz M.A., Henning H.H., Costa P.F., Malda J., Le Gac D.S., Bray F., van Duursen M.B.M., Brouwers J.F., Lest C.H.A., Bertijn I., Kraneburg L., Vos P.L.A.M., Stout T.A.E., Gadella B.A., 2018, Potential Health and Environmental Risks of Three-Dimensional Engineered Polymers, Environ. Sci. Technol. Lett., doi: 10.1021/acs.estlett.7b00495

2017

• Costa P.F., Albers H.J., Linssen J.E.A., MIddelkamp H.H.T., van der Hout L., Passier R., van den Berg A., Malda J., van der Meer A.D., 2017, Mimicking Arterial Thrombosis in a 3D-Printed Microfluidic in vitro Vascular Model Based on Computed Tomography Angiography Data, Lab on a Chip, doi: 10.1039/C7LC00202E
• Ferraz M., Henning H., Costa P.F., Malda J., Melchels F., Stout T., Vos P., Gadella B., 2017, Improved bovine embryo production in an oviduct-on-a-chip system: Prevention of polyspermic fertilization as well as parthenogenic activation, Lab on a Chip, doi: 10.1039/C6LC01566B

2016 

• Schneeberger K., Spee B., Costa P.F., Sachs N., Clevers H., Malda J., 2016, Converging biofabrication and organoid technologies: the next frontier in tissue engineering?, Biofabrication, doi: 10.1088/1758-5090/aa6121
• Carter S.D., Costa P.F., Vaquette C., Ivanovski S., Hutmacher D.W., Malda, J., 2016, Additive biomanufacturing: an advanced approach for periodontal tissue regeneration, Annals of Biomedical Engineering, doi:10.1007/s10439-016-1687-2
• Lima A.C., Alvarez-Lorenzo C., Mano J.F., 2016, Design Advances in particulate systems for biomedical applications, Adv. Healthcare Mater., 5: 1687–1723. doi:10.1002/adhm.201600219

2015

• Costa P.F., Hutmacher D.W., Theodoropoulos C., Gomes, M.E., Reis R.L., Vaquette C., 2015, Regenerative Medicine: Additively Manufactured Device for Dynamic Culture of Large Arrays of 3D Tissue Engineered Constructs, Advanced Healthcare Materials, doi: 10.1002/adhm.201570038
• Costa P.F., Puga A.M., Diaz-Gomez L., Concheiro A., Busch D.H., Alvarez-Lorenzo C., 2015, 3D printed scaffolds with controlled release of dexamethasone for bone regeneration, International Journal of Pharmaceutics. doi: 10.1016/j.ijpharm.2015.10.055
• Costa P.F., Hutmacher D.W., Theodoropoulos C., Gomes, M.E., Reis R.L., Vaquette C., 2015, Additively manufactured device for dynamic culture of large arrays of 3D tissue engineered constructs, Advanced Healthcare Materials, doi: 10.1002/adhm.201400591
• Rasche L., Duell J., Castro I.C., Dubljevic V., Chatterjee M., Knop S., Hensel F., Rosenwald A., Einsele H., Topp M.S., Brändlein S., 2015, GRP78-directed immunotherapy in relapsed or refractory multiple myeloma - results from a phase 1 trial with the monoclonal immunoglobulin M antibody PAT-SM6, Haematologica, 100(3):377-84, doi: 10.3324/haematol.2014.117945
• Lima A.C., Mano J.F., Micro/nano structured superhydrophobic surfaces in the biomedical field. Part I: basic concepts and biomimetic approaches, Nanomedicine, 2015;10:103-119
• Lima A.C., Mano J.F., Micro/nano-structured superhydrophobic surfaces in the biomedical field. Part II: applications overview, Nanomedicine, 2015;10:271-297
• Lima A.C., Mano J.F., Concheiro A., Alvarez-Lorenzo C., Fast and mild strategy, using superhydrophobic surfaces, to produce collagen/platelet lysate gel beads for skin regeneration, Stem Cells Reviews and Reports 2015;11:161-179

2014 

• Costa P.F., 2014, Bone Tissue Engineering Drug Delivery, Current Molecular Biology Reports (Inaugural Volume), doi: 10.1007/s40610-015-0016-0
• Costa P.F., 2014, Biofabricated constructs as tissue models: a short review, Journal of Materials Science: Materials in Medicine, doi: 10.1007/s10856-015-5502-7
• Costa P.F., Vaquette C., Baldwin J., Chhaya M., Gomes M.E., Reis R.L., Theodoropoulos C., Hutmacher D.W., 2014, Biofabrication of customized bone grafts by combination of additive manufacturing and bioreactor knowhow, Biofabrication, 6 035006 doi:10.1088/1758-5082/6/3/035006
• Costa P.F., Vaquette C., Zhang Q., Reis R.L., Ivanovski S., Hutmacher D.W., 2014, Advanced tissue engineering scaffold design for regeneration of the complex hierarchical periodontal structure, Journal of Clinical Periodontology, 41(3):283-94. doi: 10.1111/jcpe.12214
• Lima A.C., Puga A.M., Mano J.F., Concheiro A., Alvarez-Lorenzo C., Free and copolymerized γ-cyclodextrins regulate performance of dexamethasone-loaded dextran microspheres for bone regeneration, Journal of Materials Chemistry B 2014;2:4943-4956

2013

• Costa P.F., Martins A., Neves N.M., Gomes M.E., Reis R.L., 2013, Automating the processing steps for obtaining bone tissue engineered substitutes: from imaging tools to bioreactors, Tissue Engineering Part B: Reviews, 20(6): 567-577. doi:10.1089/ten.teb.2013.0751
• Castro I.C., Breiling A., Luetkenhaus K., Ceteci F., Hausmann S., Kress S., Lyko F., Rudel T., Rapp U.R., 2013, MYC-induced epigenetic activation of GATA4 in lung adenocarcinoma, Mol Cancer Res. 11(2):161-72, doi: 10.1158/1541-7786
• Lima A.C., Correia C.R., Oliveira M.B., Mano J.F., Sequential ionic and thermogelation of chitosan spherical hydrogels prepared using superhydrophobic surfaces to immobilize cells and drugs, Journal of Bioactive and Compatible Polymers 2013;28:50-65
• Puga A.M., Lima A.C., Mano J.F., Concheiro A., Alvarez-Lorenzo C., Pectin-coated chitosan microgels crosslinked on superhydrophobic surfaces for 5-fluorouracil encapsulation, Carbohydrate Polymers, 2013;98:331-340
• Lima A.C., Custódio C.A., Alvarez-Lorenzo C., Mano J.F., Biomimetic methodology to produce polymeric multilayered particles for biotechnological and biomedical applications, Small, 2013;9:2487-2492

2012 

• Costa P.F., Dias A., Reis R.L., Gomes M.E., 2012, Cryopreservation of cell/scaffold tissue engineered constructs, Tissue Engineering Part C: Methods, 18(11): 852-858
• Lima A.C., Batista P., Valente T.A.M., Silva A.S., Correia I.J., Mano J.F., Novel methodology based on biomimetic superhydrophobic substrates to immobilize cells and proteins in hydrogel spheres for biomedical applications, Tissue Engineering Part A. 2012;19: 1175-1187
• Lima A.C., Praveen Sher, Mano J.F., Production methodologies of polymeric and hydrogel particles for drug delivery applications, Expert Opinion on Drug Delivery, 2012;9:231-248

2011

• Goncalves M.A., Costa, P. F., Rodrigues M.T., Dias I.R., Reis R.L. and Gomes M.E., 2011, Effect of flow perfusion conditions in the chondrogenic differentiation of bone marrow stromal cells cultured onto starch based biodegradable scaffolds, Acta Biomaterialia, 7(4):1644-1652
• Lima A.C., Song W.L., Fernandez B.B., Lorenzo C.A., Mano J.F., Synthesis of temperature-responsive destran-MA/PNIPAAm particles for controlled drug delivery using supehydrophobic surfaces, Pharmaceutical Research, 2011;28:1294-305

2010

• Coutinho D.F., Costa P.F., Neves N.M., Gomes M.E. and Reis R.L., 2010, Micro and Nano Technology in Tissue Engineering, In The Tissue Engineering Book: State of the art, Visions and Limitations, eds. Pallua N, Springer
• Alves da Silva M.L., Martins A., Costa-Pinto A. R., Costa, P. F., Faria S., Gomes M.E., Reis R.L. and Neves N.M., 2010, Cartilage tissue engineering using electrospun PCL nanofiber meshes and MSCs, Biomacromolecules, 11 : 3228–3236
• Couto R.M., Simões P.C., Reis A., Da Silva T.L., Martins V.H., and Sánchez-Vicente, Y., 2010, Supercritical fluid extraction of lipids from theheterotrophic microalga Crypthecodinium cohnii, Eng. Life Sci. 10, 158–164, doi: 10.1002/elsc.200900074
• Song W.L., Lima A.C., Mano J.F., Bioinspired methodology to fabricate hydrogel spheres for multi-applications using superhydrophobic substrates, Soft Matter, 2010; 6:5868-71

2009

• Rapp U.R., Korn C., Ceteci F., Karreman C., Luetkenhaus K., Serafin V., Zanucco E., Castro I.C., Potapenko T., 2009, MYC is a metastasis gene for non-small-cell lung cancer, PLoS One, 4(6):e6029, doi: 10.1371/journal.pone.0006029
• Carvalho A.P., Martins V.H., Malcata F.X., Growth and metabolic performance of Scenedesmus pleiomorphus in biphasic bioreactors, New Biotechnology, (25), S167, doi: 10.1016/j.nbt.2009.06.531